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Clinical study · Princeton Consumer Research Corp

FOLIGAIN® TRIOXIDIL® clinical results

Visible improvements in as little as 2–4 months with the TRIOXIDIL® Shampoo, Conditioner, and Topical Treatment regimen.

Increase in visible hair volume at 4 months
180%
Fewer hairs lost while brushing at 4 months
76%
Of participants said they had more hair at 2 months
75%

Study design

How the study worked

A clinical study evaluated the cosmetic performance of the FOLIGAIN® TRIOXIDIL® regimen in men and women with self-assessed thinning hair. The regimen included TRIOXIDIL® Shampoo, Conditioner and Topical Treatment. People with a diagnosed hair loss condition, or who had used minoxidil in the past year, did not take part.

Participants used the regimen at home for four months, from January to May 2019. Results were compared with baseline, the measurements taken at the start of the study. No adverse events were reported.

Research organization
Princeton Consumer Research Corp
Study year
2019
Participants
61 adults: 30 men and 31 women
Ages
18 to 75
Who took part
Adults who reported visible thinning, reduced density, or brittle hair
Study duration
4 months of continuous use

How results were measured

The study used three evaluation methods.

  1. Clinical expert assessment

    Clinical evaluators scored visible hair attributes on a 0–5 scale. Macro photographs of a fixed scalp area were used to count visible hairs.

    Measured Shine, volume, thickness, softness, scalp health, hair strength and visible hair count

  2. Brush friction count

    A controlled brushing method collected the hairs that came out, so broken and intact hairs could be counted and compared with baseline.

    Measured Broken hairs and intact hairs collected during brushing

  3. Participant self-evaluation

    Participants answered a questionnaire about the look and feel of their own hair at month 2 and month 4.

    Measured Volume, thickness, softness, shine, hair count, hair loss, strength, breakage and scalp health

Visible changes assessed:

  • Hair volume
  • Density
  • Shine
  • Softness
  • Scalp condition
  • Breakage levels
  • Overall appearance of thinning areas

Results

What changed by month 2 and month 4

Each chart shows one of the study's methods. Bars start at zero and every value is printed beside its bar.

Clinical expert assessment

Evaluator assessment

Mean evaluator scores on a 0–5 scale, from the final study report. Every attribute improved significantly from baseline to month 4 (p<0.05); hair strength did not change by month 2.

Shine

  • Baseline: 1.79
  • Month 2: 2.97
  • Month 4: 3.95

Volume

  • Baseline: 1.52
  • Month 2: 2.92
  • Month 4: 4.26

Thickness

  • Baseline: 2.49
  • Month 2: 3.08
  • Month 4: 3.43

Softness

  • Baseline: 2.46
  • Month 2: 3.97
  • Month 4: 4.66

Scalp health

  • Baseline: 2.33
  • Month 2: 3.59
  • Month 4: 4.46

Hair strength

  • Baseline: 2.98
  • Month 2: 2.98
  • Month 4: 3.75
View the data
AttributeBaselineMonth 2Month 4
Shine1.792.973.95
Volume1.522.924.26
Thickness2.493.083.43
Softness2.463.974.66
Scalp health2.333.594.46
Hair strength2.982.983.75

Brush friction count

Less hair collected during brushing

Reduction from baseline in hairs collected during brushing.

Broken hairs

  • Month 2: −44%
  • Month 4: −76%

Intact hairs

  • Month 2: −33%
  • Month 4: −82%
View the data
AttributeMonth 2Month 4
Broken hairs−44%−76%
Intact hairs−33%−82%

Macro photography

Visible hair count

Visible hairs counted in a fixed scalp area by macro photography.

  1. Baseline126.41
  2. Month 2126.41
  3. Month 4132.56

Mean hairs counted in the same 2 cm × 2 cm scalp area. No change at month 2; a significant increase at month 4 (p<0.05). Bars start at zero.

Participant self-evaluation

Participant questionnaire

Share of participants who agreed or strongly agreed with each statement.

Volume

  • Month 2: 98.36%
  • Month 4: 100%

Thickness

  • Month 2: 98.36%
  • Month 4: 96.72%

Softness

  • Month 2: 95.08%
  • Month 4: 96.72%

Shine

  • Month 2: 93.44%
  • Month 4: 96.72%

Increased hair count

  • Month 2: 75.41%
  • Month 4: 85.25%

Decreased hair loss

  • Month 2: 80.33%
  • Month 4: 88.52%

Strength

  • Month 2: 91.80%
  • Month 4: 93.44%

Prevented hair breakage

  • Month 2: 91.80%
  • Month 4: 93.44%

Scalp health

  • Month 2: 91.80%
  • Month 4: 93.44%
View the data
Reported improvementMonth 2Month 4
Volume98.36%100%
Thickness98.36%96.72%
Softness95.08%96.72%
Shine93.44%96.72%
Increased hair count75.41%85.25%
Decreased hair loss80.33%88.52%
Strength91.80%93.44%
Prevented hair breakage91.80%93.44%
Scalp health91.80%93.44%

Source: Princeton Consumer Research Corp, final report WRGGRO1C (1 August 2019). 61 adults (30 men, 31 women) with self-assessed thinning hair used TRIOXIDIL® Shampoo, Conditioner and Topical Treatment for four months. These are cosmetic results about the look and feel of hair. Individual results vary.

Findings

What the study found

Three findings, each with the method used to measure it.

  1. Visible reduction in hair loss due to breakage

    Participants showed a significant decrease in broken and shed hairs during brushing, helping hair appear fuller and less sparse in areas affected by early stage hair loss.

    MethodBrush friction count method

  2. Improved volume, thickness and scalp appearance

    Expert evaluations confirmed noticeable improvements in visible volume, thickness, softness, shine, and overall scalp condition, supporting the look of healthier and more resilient hair.

    MethodClinical expert assessment and participant self evaluation

  3. Increased visible hair count

    Macro photography demonstrated an increase in the number of visible hairs within a measured scalp area, supporting improved density and better looking coverage in thinning zones.

    MethodMacro photography combined with expert assessment

Conclusions

Across the four month study period, clinical evaluators observed consistent improvements in multiple visible hair attributes. Shine, volume, thickness, softness, and overall scalp appearance all showed statistically significant gains at each monthly assessment.

Hair strength also improved over the full four months, and macro photographs of a fixed scalp area showed an increase in the number of visible hairs, supporting improved density and better looking coverage in areas affected by thinning or early stage hair loss.

Brush friction count data demonstrated a significant reduction in both broken hairs and intact hairs collected during brushing over the four month period, supporting less visible loss related to breakage.

Self perception questionnaires showed highly favorable responses at month four, with a majority of participants reporting improvements in the look of hair thickness, volume, scalp health, and reduced visible hair loss due to breakage.

These combined clinical and self reported findings indicate that the TRIOXIDIL® regimen provided strong cosmetic support for men and women concerned about thinning hair and early signs of hair loss.

About TRIOXIDIL®

Clinically tested cosmetic support for early stage hair loss

Only FOLIGAIN® contains TRIOXIDIL®, an advanced triple action nutrient complex developed by a team of hair care specialists. This drug free blend features natural and bioactive ingredients evaluated in cosmetic testing to support the visible concerns associated with thinning hair and early hair loss, helping improve the look of scalp coverage and hair density.

Liposphere micro emulsion technology helps TRIOXIDIL® deliver key ingredients to the scalp and hair shaft for a more effective cosmetic experience. This exclusive triple action complex includes Trichogen™, Procapil™, copper peptides, and Pisum Sativum sprout extract, all chosen to support the appearance of fuller, healthier looking hair. These ingredients have undergone rigorous testing to ensure optimal support for scalp and hair appearance.

TRIOXIDIL® was developed by the experts at FOLIGAIN® to help infuse the scalp with essential nutrients and botanicals that contribute to stronger, thicker looking hair over time.

TRIOXIDIL® is also enhanced with a proprietary moisture barrier technology that helps lock in key bioactive ingredients to support efficacy and maintain hydration on the scalp for overall skin and hair appearance.

Inside the complex

  • Trichogen™
  • Procapil™
  • Copper peptides
  • Pisum Sativum sprout extract
What is TRIOXIDIL®?
Video: how to apply FOLIGAIN® TRIOXIDIL® topical solutions

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